5-MTHF/B12 MC 2000 contains 1000 mg per serving of each folic acid and the active form of B12. Quatrefolic® from Gnosis is a new generation of folic acid. It represents a breakthrough in folate supplementation with regard to an active, stable, and highly bioavailable form when compared to folic acid and the methyl derivative folate. Quatrefolic® provides folate in the (6S)-5-methyltetrahydrofolate form which is easily utilized and stored in the body. The methylcobalamin form of B12 is the active form and does not need to be converted.